Dr. Antoni Rucinski, PhD

ORCID iD iconorcid.org/0000-0002-5815-4606     researchgate


Antoni, in the background gantry of CCB Krakow proton beam therapy centre

Education:

  • 2017 – now:  Visiting professor at IFJ PAN
  • 2015 – 2016: Postdoctoral fellow at INFN
    National Institute for Nuclear Physics, section Rome, IT
  • 2014: Clinical Medical Physicist (hospital, non-scientific position) at the Radiation Therapy Clinic, SLK-Kliniken Heilbronn, Germany
  • 2010 – 2013: Ph.D. student of Heidelberg University, DE (Medical Physics)
    University Clinic Heidelberg and Heidelberg Ion Beam Therapy Center (HIT) (pdf)
  • 2004 – 2009:  Student of Technical University of Warsaw, PL
    Master Degree in Automatics and Robotics/Medical Physics/Biomoedical Engineering

Certification:

  • Specjalista w dziedzinie fizyki medycznej (PL)
  • Qualified Medical Physicist, certified by Deutsche Geselschaft fur Medizinische Physik (DGMP)
  • Medical Physics Expert Certification, specialisations certified by Baden-Württemberg Regional Council (proton radiotherapy, photon radiotherapy, brachytherapy, nuclear medicine)

Curriculum:

My research interests serve interdisciplinary basis ranging from clinical medical physics, to nuclear physics and radiobiology modeling for clinical application. After graduating from biomedical engineering in Warsaw, I have devoted my research career to innovative developments in medical physics and in particular to charged particle therapy. My PhD was an interdisciplinary project in clinical medical physics aiming to improve proton and carbon ion radiation therapy treatment planning. I complemented my research activities in Heidelberg by medical physics training leading to a medical physics expert certification. This experience has allowed me to carry out basic research projects while understanding the clinical needs and limitations of radiation therapy.

After my clinical medical physics training I enriched my experience with a postdoctoral fellowship in nuclear physics. I used advanced experimental and computational methods to quantify secondary radiation produced during particle therapy which led to the paper series Secondary radiation measurements for particle therapy applications. These activities lead to the development of an ion beam range monitor (INFN Dose Profiler). This detector is currently tested in clinical trials in the carbon ion therapy facility in Italy (CNAO) and is expected to improve the accuracy of patient treatments.

From January 2017 I am employed as a researcher in the Institute of Nuclear Physics IFJ PAN in Krakow (Adjunct, Visiting Professor, now Institute Professor). I am PI of two research projects funded by Polish funding agencies (Foundation of Polish Science and National Centre for Research and Development) and I am leading a research group of 5 researchers, co-supervise PhD students and guide a few technicians. Both projects have interdisciplinary character and aim at translation of developed techniques to proton therapy clinical routine. They are performed in collaboration with excellent international research partners from top, world-wide recognized Universities, research Institutes and radiotherapy facilities.

The objective of the first project is commissioning and clinical validation of a GPU-accelerated Monte Carlo based treatment planning system with the goal of clinical quantification of biological dose uncertainties resulting from application of existing RBE models. Employing Monte Carlo simulations for independent treatment plan verification will improve quality assurance of patient treatment plans. The system is equipped with radiobiological modeling tools that can be used to support treatment planning by accounting for variable radiobiological effectiveness of protons that is currently not considered in the commercial treatment planning systems. The project proposal was awarded with prestigious Marie Sklodowska-Curie Actions Seal of Excellence certification.

The objective of the second project is to develop range monitoring methods for proton beam therapy based on novel, plastic scintillator-based positron emission tomography technology (J-PET) developed at the Jagiellonian University (UJ) in Krakow. Within this project I have established a very fruitful collaboration with Prof. Pawel Moskal research group (UJ). In the frame of this project we have been performing first world-wide simulations and experimental tests to assess feasibility of J-PET detector technique to monitor proton beam therapy treatments by determination of proton beam range in-vivo.

In parallel to above research activities over the last years I dedicate my time to develop management skills and applied marketing knowledge that can improve my understanding of how to incorporate scientific innovation in the industry. In 2018 I participated in a prestigious training, MIT/HMS Healthcare Innovation Bootcamp organized jointly by Massachusetts Institute of Technology and Harvard Medical School in Boston, US, which strengthen my managerial skills and made me familiar with world innovation ecosystem.

Publications:

Without PhD project supervisor:

  1. A. Rucinski, A. Biernacka, R. Schulte. Applications of Nanodosimetry in Particle Therapy Planning and Beyond. To be submitted to PMB (pdf).
  2. M. Garbacz, …, A. Rucinski (last author) et al. Quantification of biological range uncertainties towards an improved patient treatment in CCB Cracow proton beam therapy centre. To be submitted to Green Journal (2020)
  3. M. Garbacz, …, A. Rucinski (last author) et al. Dose recalculations with variable RBE model of skull base patients plans treated with proton therapy – a retrospective study. To be submitted to Green Journal (2020)
  4. J. Gajewski, …, A. Rucinski (last author) et al. Commissioning and clinical validation of GPU-accelerated Fred Monte Carlo code for proton beam therapy. Submitted to Frontiers in Physics, 2020. (pdf)
  5. J. Gajewski, …, A. Rucinski, …, et al. A GPU Monte Carlo to support clinical routine in a compact spot scanning proton therapy system. Submitted to Frontiers in Physics, 2020. (pdf)
  6. P. Stasica, …, A. Rucinski, …, et al. A simple approach for experimental characterization and validation of proton pencil beam profiles. Accepted in Frontiers in Physics (pdf)
  7. C. Granja,  …, A. Rucinski, …, et al. Wide-Range Tracking and LET-Spectra of Energetic Light and Heavy Charged Particles. Submitted to NIMA (pdf)
  8. K. Czerska, …, A. Rucinski (last author) et al. Clinical practice vs. state-of-the-art research and future visions: 4D workshop report edition 2018 and 2019. Submitted to Physica Medica (pdf)
  9. A. Rucinski, et al. Investigations on physical and biological range uncertainties in Krakow proton beam therapy centre. Acta Physica Polonica B. doi
  10. A.  Wronska, A. Rucinski, Wyzwania w terapii protonowej – jak leczyć nowotwory lepiej? Rozdział Monografii naukowej:  Nowoczesne technologie XXI w. – przegląd, trendy i badania. Tom 1, Wydawnictwo Naukowe TYGIEL link
  11. Trnková, …, A. Rucinski, …, et al. Clinical implementations of 4D pencil beam scanned particle therapy: Report on the 4D treatment planning workshop 2016 and 2017. Physica Medica: European Journal of Medical Physics 2018 54:121–130 doi
  12. Rucinski, …, et al. Secondary radiation measurements for particle therapy applications: charged secondary produced by 16O beams in a PMMA target at large angle. Physica Medica: European Journal of Medical Physics 64:45-53. 2019 doi
  13. Rucinski, …, et al. Secondary radiation measurements for particle therapy applications: charged secondary produced by 4He and 12C beams in a PMMA target at large angle. Phys. Med. Biol. 63(5):055018. 2018 doi
  14. Mattei, …, A. Rucinski, …, et al. Addendum: Measurement of charged particle yields from PMMA irradiated by a 220 MeV/u 12C beam. Phys. Med. Biol.62:8483 doi
  15. Mattei, …, A. Rucinski, …, et al. Secondary radiation measurements for particle therapy applications: prompt gamma produced by 4He, 12C and 16O beams in a PMMA target. Phys. Med. Biol. 62 (4), 1438-1455. 2017 doi
  16. Marafini, …, A. Rucinski, …, et al. Secondary radiation measurements for particle therapy applications: nuclear fragmentation produced by 4He ion beam in a PMMA target 62 (4), 1291-1309. 2017 doi
  17. Traini, …, A. Rucinski, …, et al. Design of a new tracking device for on-line dose monitor in hadron therapy Physica Medica: European Journal of Medical Physics 34:18-27. 2017 doi
  18. Muraro, …, A. Rucinski, …, et al. Monitoring of hadrontherapy treatments by means of charged particle detection.Frontiers in Oncology 2016 6(15) doi
  19. Knopf, …, A. Rucinski, …, et al. Required transition from research to clinical application: report on the 4D treatment planning workshops 2014 and 2015. Physica Medica: European Journal of Medical Physics. 2016 32:874 doi
  20. Solfaroli Camillocci, …, A. Rucinski, Intraoperative probe detecting β− decays in brain tumour radio-guided surgery, Nucl. Instr. Meth. Phys. Res. A 2016 doi
  21. Mattei, …, A. Rucinski, et al. Prompt-gamma production of 220 MeV/u 12C ions interacting with a PMMA target. The Journal of Instrumentation 2015 10 doi
  22. Knopf, …, A. Rucinski, …, et al. Challenges of radiotherapy: Report on the 4D treatment planning workshop 2013. Physica Medica 2014 11 doi

With PhD project supervisor:

  1. Rucinski, …, et al. Preclinical investigations towards the first spacer gel application in prostate cancer treatment during particle therapy at HIT. Radiation Oncology 2013 8:134 doi
  2. Rucinski, …, et al. Ion therapy of prostate cancer: daily rectal dose reduction by application of spacer gel. Radiation Oncology 2015 10:56 doi
  3. S. Hild, …, A. Rucinski, et al. Scanned ion beam therapy for prostate carcinoma: Comparison of single plan treatment and daily plan-adapted treatment. Strahlentherapie und Onkologie 2016 192(2) doi

Invited presentations to internationally established conferences
Only oral presentations listed.

Without PhD project supervisor:

  1. Rucinski, …, et al. MO-K-301-6: GPU-Accelerated Monte Carlo Code FRED for Clinical Application in Proton Therapy.AAPM Annual Meeting 2019, San Antonio, TX, USA; Conference program Medical Physics 46(6):2782-2883 doi
  2. Rucinski, …, et al. Investigations on physical and biological range uncertainties in Krakow proton beam therapy centre.3rd Jagiellonian Symposium on Fundamental and Applied Subatomic Physics, 2019, Krakow, Poland;
  3. Rucinski, …, et al. MIC-WS1 II-05: Plastic scintillator based PET detector technique for proton therapy range monitoring. A Monte Carlo study. (#2989) 2018 IEEE Nuclear Science Symposium and Medical Imaging Conference, Sydney, Australia; Conference Record doi
  4. Rucinski, …, et al. Proton therapy treatment plan verification in CCB Krakow using Fred Monte Carlo TPS tool, IUPESM World Congress 2018, Prague, Czech Republic
  5. Rucinski, …, et al. Implementation and validation of clinical proton beam model in GATE and GPU-accelerated MC code Fred for quality assurance and detector development applications, Third Geant4 International User Conference at the Physics-Medicine-Biology frontier 2018, Bordeaux, France
  6. Rucinski, …, et al. GPU-accelerated Monte Carlo code for fast dose recalculation in proton beam therapy. 2nd Jagiellonian Symposium on Fundamental and Applied Subatomic Physics 2017, Krakow, Poland Acta Physica Polonica B 48(10). (proceeding: doi)
  7. Rucinski, et al., in Proceedings of the 14th International Conference on Nuclear Reaction Mechanisms, edited by F. Cerutti, M. Chadwick, A. Ferrari, T. Kawano and P. Schoofs, CERN-Proceedings- 2015-001 (CERN, Geneva, 2015), pp. 355-360: Measurements of secondary particles emitted by 4He, 12C and 16O ion beams in view of innovative dose profiling technique in Particle Therapy. (proceeding)

With PhD project supervisor:

  1. Rucinski, et al. Initial qualification of the irradiation uncertainties in ion beam therapy of prostate cancer. International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe, ICTR-PHE, Geneva, Switzerland. Radiotherapy and Oncology 2014 110 Suppl.1:83 doi
  2. Rucinski, et al. Target volume optimization for prostate cancer treatment in carbon ion radiation therapy in the presence of interfractional motion. International Conference on Translational Research in Radio-Oncology and Physics for Health in Europe, ICTR-PHE, Geneva, Switzerland. Radiotherapy and Oncology 2012 102 Suppl.1:81 doi

Invited seminars:

  1. Physical and biological range uncertainties in proton and ion beam therapy. Strathclyde Intense Laser Interaction Studies (SILIS) Group, University of Strathclyde, Glasgow, Scotland, 16/11/2017
  2. Physical and biological range uncertainties in proton and ion beam therapy. Biomedical Physics Division, Faculty of Physics, University of Warsaw, Poland, 6/04/2017
  3. Physical and biological range uncertainties in proton and ion beam therapy. Institute of Nuclear Physics PAN, Krakow, Poland, 25/01/2017
  4. Treatment planning and range monitoring in ion beam therapy. Massachusetts General Hospital (MGH), Harvard Medical School, Boston, USA. 26/07/2016
  5. Secondary radiation measurements for particle therapy applications. Institute of Nuclear Physics of Lyon (IPNL), Lyon, France. 05/07/2016 (link)
  6. Hadrontherapy: treatment of moving organs and in-vivo imaging for dose distribution monitoring (Terapia hadronowa: leczenie poruszajacych sie organow i obrazowanie in-vivo w celu monitoriwania rozkladu dawki). Seminar at the annual meeting of Committee for Medical Physics, Radiobiology and Diagnostic Imaging of Polish Academy of Science (Komitet Fizyki Medycznej, Radiobiologii i Diagnostyki Obrazowej Polskiej Akademii Nauk). Warsaw, Poland. 09/04/2014
  7. Organ motion management for optimisation of fractionated ion therapy of prostate cancer at HIT. Institute of Nuclear Physics PAN, Krakow, Poland. 13/07/2013
  8. Organ motion management for optimisation of fractionated ion therapy of prostate cancer at HIT. Marburger Ionenstrahl-Therapiezentrum (MIT), Marburg, Germany. 24/06/2013

Referee:

PlosONE, Acta Physica Polonica B, ACTA ONCOLOGICA, Medical Physics, Radiotherapy and Oncology.

Languages:

  • Polish (mother tongue)
  • English (proficient)
  • German (proficient)
  • Italian (basic)